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Snapshot · OMB 2025 inventory · processed Oct 11, 2026
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AI use cases

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Agency: DOE · Department of EnergyAI type: Classical / predictive MLTopic: Science
Columns (7)
Use caseAgencyStageHigh-impactTopic areaAI classificationSourcing
Physics-Informed Learning Machines for Multiscale and Multiphysics Problems (PhILMs)
DOE-356 · PNNL - Pacific Northwest National Laboratory (SC43 OIM)
DOEDeployedNot high-impactScienceClassical / predictive MLDeveloped in-house
high level synthesis for machine learning (previously hls4ml)
DOE-64 · FNAL - Fermi National Accelerator (SC43 OIM)
DOEDeployedNot high-impactScienceClassical / predictive MLDeveloped in-house
READS: Real-time Edge AI for Distributed Systems
DOE-70 · FNAL - Fermi National Accelerator (SC43 OIM)
DOEDeployedNot high-impactScienceClassical / predictive MLDeveloped in-house
MI8 Collimators Surogate Model
DOE-453 · FNAL - Fermi National Accelerator (SC43 OIM)
DOEPilotNot high-impactScienceClassical / predictive MLDeveloped in-house
NIF Shot Analytics & Predictive Maintenance Support Pilot
DOE-529 · LLNL - Lawrence Livermore National Laboratory (LFO)
DOEPilotNot high-impactScienceClassical / predictive MLPurchased from vendor
Machine Learning for Linac Improved Performance
DOE-60 · FNAL - Fermi National Accelerator (SC43 OIM)
DOEPilotNot high-impactScienceClassical / predictive MLDeveloped in-house
In-pixel AI for future tracking detectors
DOE-66 · FNAL - Fermi National Accelerator (SC43 OIM)
DOEPilotNot high-impactScienceClassical / predictive MLDeveloped in-house
SONIC: AI acceleration as a service
DOE-67 · FNAL - Fermi National Accelerator (SC43 OIM)
DOEPilotNot high-impactScienceClassical / predictive MLDeveloped in-house
Denoising Diffusion to Accelerate Detector Simulation
DOE-716 · FNAL - Fermi National Accelerator (SC43 OIM)
DOEPilotNot high-impactScienceClassical / predictive MLDeveloped in-house
Machine Learning for Accelerator Operations Using Big Data Analytics / L-CAPE
DOE-73 · FNAL - Fermi National Accelerator (SC43 OIM)
DOEPilotNot high-impactScienceClassical / predictive MLDeveloped in-house
Safeguards Digital Twin
DOE-564 · NE INL - NE Idaho National Laboratory (NE)
DOEPilotNot high-impactScienceClassical / predictive MLContract and in-house
AGN-201 DT
DOE-624 · NE INL - NE Idaho National Laboratory (NE)
DOEPilotNot high-impactScienceClassical / predictive MLContract and in-house
APT Analytics
DOE-352 · PNNL - Pacific Northwest National Laboratory (SC43 OIM)
DOEPre-deploymentNot high-impactScienceClassical / predictive MLContract and in-house
AI techniques for identification of suitable delivery parking spaces in an urban scenario
DOE-360 · PNNL - Pacific Northwest National Laboratory (SC43 OIM)
DOEPre-deploymentNot high-impactScienceClassical / predictive MLContract and in-house
Surrogate models for probabilistic Bayesian inference
DOE-361 · PNNL - Pacific Northwest National Laboratory (SC43 OIM)
DOEPre-deploymentNot high-impactScienceClassical / predictive MLDeveloped in-house
Unleashing AI Transformer Models on FPGAs for Accelerating LHC and Particle Physics
DOE-485 · FNAL - Fermi National Accelerator (SC43 OIM)
DOEPre-deploymentNot high-impactScienceClassical / predictive MLNot reported
In-storage computing for multi-messenger astronomy in neutrino experiments and cosmological surveys
DOE-63 · FNAL - Fermi National Accelerator (SC43 OIM)
DOEPre-deploymentNot high-impactScienceClassical / predictive MLNot reported
Streamining intelligent detectors for sPHENIX/EIC
DOE-65 · FNAL - Fermi National Accelerator (SC43 OIM)
DOEPre-deploymentNot high-impactScienceClassical / predictive MLNot reported
Uncertainty Quantification and Instrument Automation to enable next generation cosmological discoveries
DOE-69 · FNAL - Fermi National Accelerator (SC43 OIM)
DOEPre-deploymentNot high-impactScienceClassical / predictive MLNot reported
Simulation-based inference for cosmology
DOE-71 · FNAL - Fermi National Accelerator (SC43 OIM)
DOEPre-deploymentNot high-impactScienceClassical / predictive MLNot reported
Extreme data reduction for the edge
DOE-72 · FNAL - Fermi National Accelerator (SC43 OIM)
DOEPre-deploymentNot high-impactScienceClassical / predictive MLNot reported
ORNL: AI for Transportation and Mobility
DOE-331 · ORNL - Oak Ridge National Laboratory (SC43 OIM)
DOEPre-deploymentHigh-impactScienceClassical / predictive MLNot reported
ORNL: AI for Energy Generation and Distribution
DOE-333 · ORNL - Oak Ridge National Laboratory (SC43 OIM)
DOEPre-deploymentHigh-impactScienceClassical / predictive MLNot reported
ORNL: AI for Advanced Manufacturing
DOE-334 · ORNL - Oak Ridge National Laboratory (SC43 OIM)
DOEPre-deploymentHigh-impactScienceClassical / predictive MLNot reported
ORNL: AI for Neutron Science
DOE-338 · ORNL - Oak Ridge National Laboratory (SC43 OIM)
DOEPre-deploymentHigh-impactScienceClassical / predictive MLNot reported
ORNL: AI for Fusion Energy
DOE-340 · ORNL - Oak Ridge National Laboratory (SC43 OIM)
DOEPre-deploymentHigh-impactScienceClassical / predictive MLNot reported
Advanced Peer to Peer Transactive Energy Platform with Predictive Optimization
DOE-506 · BNL - Brookhaven National Laboratory (SC43 OIM)
DOEPre-deploymentNot high-impactScienceClassical / predictive MLNot reported
Nanoparticle growth kinetics and mechanism
DOE-513 · BNL - Brookhaven National Laboratory (SC43 OIM)
DOEPre-deploymentNot high-impactScienceClassical / predictive MLNot reported
Center for Mesoscale Transport Properties
DOE-516 · BNL - Brookhaven National Laboratory (SC43 OIM)
DOEPre-deploymentNot high-impactScienceClassical / predictive MLNot reported
Develop a Machine Learning Framework for Optimal Computational Campaigns for Complex Uncertain Systems
DOE-517 · BNL - Brookhaven National Laboratory (SC43 OIM)
DOEPre-deploymentNot high-impactScienceClassical / predictive MLNot reported
AI/ML in High Energy Physics Research
DOE-523 · BNL - Brookhaven National Laboratory (SC43 OIM)
DOEPre-deploymentNot high-impactScienceClassical / predictive MLNot reported
SMMM
DOE-533 · BNL - Brookhaven National Laboratory (SC43 OIM)
DOEPre-deploymentNot high-impactScienceClassical / predictive MLNot reported
A Digital Twin for In-silico Spatiotemporally-resolved Experiments
DOE-553 · BNL - Brookhaven National Laboratory (SC43 OIM)
DOEPre-deploymentNot high-impactScienceClassical / predictive MLNot reported
Machine learning for accelerated understanding of dynamic catalysis
DOE-554 · BNL - Brookhaven National Laboratory (SC43 OIM)
DOEPre-deploymentNot high-impactScienceClassical / predictive MLNot reported
Use AI/ML ML to Optimize Data and Experiments at National Synchrotron Light Source II (NSLS-II) and the Accelerator Test Facility (ATF)
DOE-565 · BNL - Brookhaven National Laboratory (SC43 OIM)
DOEPre-deploymentNot high-impactScienceClassical / predictive MLNot reported
Data-Science Enabled, Robust and Rapid MeV Ultrafast Electron Diffraction System to Characterize Materials Including for Quantum and Energy Applications
DOE-570 · BNL - Brookhaven National Laboratory (SC43 OIM)
DOEPre-deploymentNot high-impactScienceClassical / predictive MLNot reported
Use ML as part of an integrated strategy for forecasting renewable energy resources
DOE-572 · BNL - Brookhaven National Laboratory (SC43 OIM)
DOEPre-deploymentNot high-impactScienceClassical / predictive MLNot reported
MR-DT
DOE-579 · NE INL - NE Idaho National Laboratory (NE)
DOEPre-deploymentPresumed high-impact, determined notScienceClassical / predictive MLNot reported
Development of a Planning, Operation, and Control Framework for Hybrid Energy Storage and Renewable Generation Systems
DOE-582 · BNL - Brookhaven National Laboratory (SC43 OIM)
DOEPre-deploymentNot high-impactScienceClassical / predictive MLNot reported
Accelerated Nanomaterial Discovery
DOE-585 · BNL - Brookhaven National Laboratory (SC43 OIM)
DOEPre-deploymentNot high-impactScienceClassical / predictive MLNot reported
Use AI/ML for Climate Prediction
DOE-592 · BNL - Brookhaven National Laboratory (SC43 OIM)
DOEPre-deploymentNot high-impactScienceClassical / predictive MLNot reported
Storage usage effectiveness and data placement optimization at Data Center
DOE-600 · BNL - Brookhaven National Laboratory (SC43 OIM)
DOEPre-deploymentNot high-impactScienceClassical / predictive MLNot reported
Objective-Driven Data Reduction for Scientific Workflows
DOE-612 · BNL - Brookhaven National Laboratory (SC43 OIM)
DOEPre-deploymentNot high-impactScienceClassical / predictive MLNot reported
Autonomous, real-time guiding of BCP film synthesis
DOE-614 · BNL - Brookhaven National Laboratory (SC43 OIM)
DOEPre-deploymentNot high-impactScienceClassical / predictive MLNot reported
Low Dose Radiation Biology
DOE-617 · BNL - Brookhaven National Laboratory (SC43 OIM)
DOEPre-deploymentNot high-impactScienceClassical / predictive MLNot reported
KBase: An Integrated Knowledgebase for Predictive Biology and Environmental Research
DOE-619 · BNL - Brookhaven National Laboratory (SC43 OIM)
DOEPre-deploymentNot high-impactScienceClassical / predictive MLNot reported
lntegrated Platform for Multimodal Data Capture, Exploration and Discovery Driven by Al Tools
DOE-627 · BNL - Brookhaven National Laboratory (SC43 OIM)
DOEPre-deploymentNot high-impactScienceClassical / predictive MLNot reported
Accelerating HEP Science: Inference and Machine Learning at Extreme Scales
DOE-644 · BNL - Brookhaven National Laboratory (SC43 OIM)
DOEPre-deploymentNot high-impactScienceClassical / predictive MLNot reported
Continuous Structure Descriptors for XANES Interpretation
DOE-655 · BNL - Brookhaven National Laboratory (SC43 OIM)
DOEPre-deploymentNot high-impactScienceClassical / predictive MLNot reported
Machine Learning for Autonomous Control of Scientific User Facilities
DOE-663 · BNL - Brookhaven National Laboratory (SC43 OIM)
DOEPre-deploymentNot high-impactScienceClassical / predictive MLNot reported
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