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Snapshot · OMB 2025 inventory · processed Oct 11, 2026
HHS · no agency ID · record R0968

Pangolin Lineage Classification of SARS-CoV-2 Genome Sequences

Department of Health and Human Services · HHS/NIH

Overview

Development stage
DeployedSource: c) Deployed – The use case is being actively authorized or utilized to support the functions or mission of an agency.
High-impact designation
Not high-impactSource: c) Not high-impact
Impact justification
Not reported
Start date
2021-04 (month precision)Source: Apr-21
Withheld from public reporting
NoSource: a) No

Mission

Topic area
Science
Operational functions
No function tag matched Derived by keyword rules; see methodology

Problem the AI is intended to solve

Process a high volume of sequence data in real time to identify meaningful mutational patterns while minimizing the need for human effort.

Expected benefits

Improved user retrieval of SARS-CoV-2 genome sequences based on classification and tracking of specific lineages, including those associated with mutations that may decrease effectiveness of therapeutics or protection provided by vaccination.?

System outputs

Lineage classification identifiers for sequences

Technology

AI classification
Classical / predictive MLSource: Classical/Predictive Machine Learning: Models trained on data to make predictions or classifications based on identified patterns or relatio…
System name(s)
Not reported
Custom-developed code
No
Public source code
github.com ↗

Sourcing

How it was built
Purchased from vendorSource: a) Purchased from a vendor
Vendor (as reported)
http://cov-lineages.org; https://pangolin.cog-uk.io/
Vendors (standardized)
None on the standard list

A vendor is the supplier named by the agency. It does not identify the underlying model or AI technology.

Data and privacy

Involves PII
No
Privacy Impact Assessment
Not reported
Authorization to Operate
No
Demographic features
k) None of the above
Training and evaluation data
Publicly available SARS-CoV-2 sequence data from the GenBank resource was used to develop the tool
Federal Data Catalog
Not reported

Governance

0 of 8 minimum-practice questions answered. A blank answer means the agency reported nothing; it does not mean the practice is absent.

Pre-deployment testingNo answer reported
AI impact assessmentNo answer reported
Independent reviewNo answer reported
Ongoing monitoringNo answer reported
Operator trainingNo answer reported
Fail-safeNo answer reported
Appeal processNo answer reported
User and public consultationNo answer reported

Potential impacts and how they were identified

Not reported