AI Use Cases

Use case	Agency	Stage	High-impact	Topic area	AI classification	Sourcing
Malaria parasites DNA barcode geography classification R0658 · HHS/CDC	HHS	Deployed	Not high-impact	Health and Medical	Classical / predictive ML	Developed in-house
Genetic distance computation method for comparing complex multi-locus parasite (Cyclospora) genotypes R0673 · HHS/CDC	HHS	Deployed	Not high-impact	Health and Medical	Classical / predictive ML	Developed in-house
NIOSH Industry and Occupation Computerized Coding System (NIOCCS) R0676 · HHS/CDC	HHS	Deployed	Not high-impact	Administrative Functions	Classical / predictive ML	Developed in-house
Nowcasting Injury Trends R0677 · HHS/CDC	HHS	Deployed	Not high-impact	Health and Medical	Classical / predictive ML	Developed in-house
Machine Learning with Premier Healthcare Data to inform predictive modeling of antibiotic use R0695 · HHS/CDC	HHS	Deployed	Not high-impact	Health and Medical	Classical / predictive ML	Developed in-house
Machine Learning Techniques for Early Detection and Situational Awareness of Rabies Outbreaks R0696 · HHS/CDC	HHS	Deployed	Not high-impact	Health and Medical	Classical / predictive ML	Developed in-house
Lineage Assignment by Extended Learning (LABEL) R0717 · HHS/CDC	HHS	Deployed	Not high-impact	Science	Classical / predictive ML	Developed in-house
Supply Chain Resilience Program, Office of Supply Chain Resilience (OSCR) - Foresight R0833 · HHS/FDA/CDRH	HHS	Deployed	Not high-impact	Health and Medical	Classical / predictive ML	Developed in-house
CDER Regulatory Science Research (RSR) Projects AI for Process Control in Advanced Manufacturing R0837 · HHS/FDA/CDER	HHS	Deployed	Presumed high-impact, determined not	Science	Classical / predictive ML	Developed in-house
Food AI Decision Engine (FAIDE) R0863 · HHS/FDA/HFP	HHS	Deployed	Not high-impact	Health and Medical	Classical / predictive ML	Developed in-house
Rapid Intuitive Pathogen Surveillance (RIPS) R0865 · HHS/FDA/HFP	HHS	Deployed	Not high-impact	Health and Medical	Classical / predictive ML	Developed in-house
Biomedical Citation Selector (BmCS) R0907 · HHS/NIH	HHS	Deployed	Not high-impact	Administrative Functions	Classical / predictive ML	Developed in-house
Medical Text Indexer-NeXt Generation (MTIX) MEDLINE Indexing R0923 · HHS/NIH	HHS	Deployed	Not high-impact	Administrative Functions	Classical / predictive ML	Developed in-house
NICHD RPAB AI/ML Application Referral System R0930 · HHS/NIH	HHS	Deployed	Presumed high-impact, determined not	Administrative Functions	Classical / predictive ML	Developed in-house
NLP Automated Referral R0931 · HHS/NIH	HHS	Deployed	Presumed high-impact, determined not	Administrative Functions	Classical / predictive ML	Developed in-house
Tool for PO Lookup Assignment (TPAL) R0946 · HHS/NIH	HHS	Deployed	Not high-impact	Administrative Functions	Classical / predictive ML	Developed in-house
Autocoding to Support Adverse Drug Event Surveillance R0662 · HHS/CDC	HHS	Pilot	Not high-impact	Administrative Functions	Classical / predictive ML	Developed in-house
Distiller SR: AI to screen research articles for Community Guide reviews R0665 · HHS/CDC	HHS	Pilot	Not high-impact	Administrative Functions	Classical / predictive ML	Developed in-house
Determining if multiple isolates share the same antimicrobial resistant plasmids using short read whole genome sequencing data R0703 · HHS/CDC	HHS	Pilot	Not high-impact	Science	Classical / predictive ML	Developed in-house
Enhancing influenza A risk assessment rubrics: leveraging predictive correlates and machine learning from in vivo experiments. R0718 · HHS/CDC	HHS	Pilot	Not high-impact	Science	Classical / predictive ML	Developed in-house
Drug Shortage Predictive Model R0840 · HHS/FDA/CDER	HHS	Pilot	Not high-impact	Health and Medical	Classical / predictive ML	Developed in-house
NICHD RPAB AI/ML NICHD Relevance Model R0901 · HHS/NIH	HHS	Pilot	Presumed high-impact, determined not	Administrative Functions	Classical / predictive ML	Developed in-house