AI Use Cases

Use case	Agency	Stage	High-impact	Topic area	AI classification	Sourcing
Independent Dispute Resolution (IDR) Eligibility Rules Engine R0757 · HHS/CMS/CCIIO	HHS	Deployed	Not high-impact	Service Delivery	Classical / predictive ML	Purchased from vendor
Docketscope Public Comment Processing R0762 · HHS/CMS/CM	HHS	Deployed	Not high-impact	Administrative Functions	Classical / predictive ML	Purchased from vendor
Developing an Objective and Quantitative Endpoint for Atopic Dermatitis in Pediatric and Adult Populations R0839 · HHS/FDA/CDER	HHS	Deployed	Presumed high-impact, determined not	Health and Medical	Classical / predictive ML	Purchased from vendor
Alphafold R0956 · HHS/NIH	HHS	Deployed	Not high-impact	Science	Classical / predictive ML	Purchased from vendor
CryoSPARC R0960 · HHS/NIH	HHS	Deployed	Not high-impact	Science	Classical / predictive ML	Purchased from vendor
ModelAngelo R0966 · HHS/NIH	HHS	Deployed	Not high-impact	Science	Classical / predictive ML	Purchased from vendor
Pangolin Lineage Classification of SARS-CoV-2 Genome Sequences R0968 · HHS/NIH	HHS	Deployed	Not high-impact	Science	Classical / predictive ML	Purchased from vendor
AWS Kendra Search tool R1042 · HHS/SAMHSA	HHS	Deployed	Not high-impact	Administrative Functions	Classical / predictive ML	Purchased from vendor
Production Operations Anomaly Analysis R0811 · HHS/CMS/OIT	HHS	Pilot	Not high-impact	Information Technology	Classical / predictive ML	Purchased from vendor